{"id":16415,"date":"2025-07-25T10:00:56","date_gmt":"2025-07-25T01:00:56","guid":{"rendered":"https:\/\/www.acacia-no-ki.co.jp\/wellness\/?p=16415"},"modified":"2025-07-25T08:38:03","modified_gmt":"2025-07-24T23:38:03","slug":"%e3%80%8c%e3%81%aa%e3%82%93%e3%81%a8%e3%81%aa%e3%81%8f%e6%af%8e%e6%97%a5%e9%a3%b2%e3%82%93%e3%81%a7%e3%81%84%e3%82%8b%e3%82%b3%e3%83%bc%e3%83%92%e3%83%bc%e3%80%81%e6%9c%ac%e5%bd%93%e3%81%ab%e4%bd%93","status":"publish","type":"post","link":"https:\/\/www.acacia-no-ki.co.jp\/wellness\/coffee-health-effect","title":{"rendered":"\u300c\u306a\u3093\u3068\u306a\u304f\u6bce\u65e5\u98f2\u3093\u3067\u3044\u308b\u30b3\u30fc\u30d2\u30fc\u3001\u672c\u5f53\u306b\u4f53\u306b\u3044\u3044\u306e\uff1f\u300d\u3068\u611f\u3058\u3066\u3044\u308b\u3042\u306a\u305f\u3078\u3002"},"content":{"rendered":"

\u30b3\u30fc\u30d2\u30fc\u306e\u52b9\u679c\u3068\u5065\u5eb7\u3078\u306e\u5f71\u97ff<\/h2>\n

\u30b3\u30fc\u30d2\u30fc \u52b9\u679c\uff5c\u52b9\u80fd\u00a0 \u79d1\u5b66\u7684\u306b\u8a8d\u3081\u3089\u308c\u305f\u4e3b\u306a\u5065\u5eb7\u52b9\u679c\u3068\u306f\uff1f<\/h3>\n

\"\"<\/h4>\n

\u6297\u9178\u5316\u4f5c\u7528\u304c\u3042\u308a\u3001\u5065\u5eb7\u7dad\u6301\u3084\u4f53\u306e\u6a5f\u80fd\u3092\u5b88\u308b\u52b9\u679c\u304c\u671f\u5f85\u3055\u308c\u308b<\/h4>\n

\u30b3\u30fc\u30d2\u30fc\u306b\u306f\u300c\u30af\u30ed\u30ed\u30b2\u30f3\u9178\u300d\u306a\u3069\u306e\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u304c\u305f\u304f\u3055\u3093\u542b\u307e\u308c\u3066\u304a\u308a\u3001\u4f53\u306e\u30b5\u30d3\u3068\u8a00\u308f\u308c\u308b\u6d3b\u6027\u9178\u7d20\u3092\u53d6\u308a\u9664\u304f\u201c\u6297\u9178\u5316\u4f5c\u7528\u201d<\/strong>\u304c\u3042\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u3053\u306e\u6297\u9178\u5316\u4f5c\u7528\u306b\u3088\u3063\u3066\u3001\u7d30\u80de\u306e\u8001\u5316\u3092\u9632\u304e\u3001\u5065\u5eb7\u7dad\u6301\u3084\u4f53\u306e\u6a5f\u80fd\u3092\u5b88\u308b\u52b9\u679c\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u8840\u7cd6\u4e0a\u6607\u30ea\u30b9\u30af\u3092\u4f4e\u4e0b\u3055\u305b\u308b<\/h4>\n

\u30aa\u30e9\u30f3\u30c0\u306e\u30d5\u30ea\u30fc\u5927\u5b66\u30a2\u30e0\u30b9\u30c6\u30eb\u30c0\u30e0\u306e\u7814\u7a76\u306b\u3088\u308b\u3068\u3001\u30b3\u30fc\u30d2\u30fc\u3092\u65e5\u5e38\u7684\u306b\u98f2\u3080\u7fd2\u6163\u304c\u3042\u308b\u4eba\u3067\u306f\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u52b9\u304d\u304c\u60aa\u304f\u306a\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u8840\u7cd6\u304c\u4e0a\u6607\u3057\u3084\u3059\u304f\u306a\u308b\u3001\u4ee3\u8b1d\u6027\u306e\u7570\u5e38\u3092\u767a\u75c7\u3059\u308b\u30ea\u30b9\u30af\u304c\u3001\u6700\u5927\u306720\u301c30\uff05\u4f4e\u4e0b\u3059\u308b<\/strong>\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

van Dam & Hu, 2005, JAMA<\/a><\/p>\n

\u809d\u81d3\u6a5f\u80fd\u3092\u4fdd\u8b77\u3059\u308b<\/h4>\n

\u8907\u6570\u306e\u7814\u7a76\u7d50\u679c\u3092\u7d71\u5408\u3057\u3066\u5206\u6790\u3059\u308b\u300c\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u300d\u306e\u7d50\u679c\u3067\u306f\u30011\u65e52\u301c3\u676f\u306e\u30b3\u30fc\u30d2\u30fc\u3092\u98f2\u3080\u7fd2\u6163\u306f\u3001\u809d\u81d3\u306e\u6a5f\u80fd\u3092\u30b5\u30dd\u30fc\u30c8\u3057\u3001\u5c06\u6765\u7684\u306a\u5065\u5eb7\u30ea\u30b9\u30af\u3092\u4e0b\u3052\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b<\/strong>\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n

Dose\u2013response \u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\uff082018\uff09<\/a><\/p>\n

Kennedy et al.\uff082016\uff09\u3001Alimentary Pharmacology & Therapeutics<\/a><\/p>\n

\u8a8d\u77e5\u6a5f\u80fd\u306e\u4f4e\u4e0b\u3092\u6291\u3048\u3001\u8133\u306e\u5065\u5eb7\u3092\u5b88\u308b\u3053\u3068\u304c\u671f\u5f85\u3067\u304d\u308b<\/h4>\n

\u30d5\u30a3\u30f3\u30e9\u30f3\u30c9\u3067\u884c\u308f\u308c\u305f\u9577\u671f\u8ffd\u8de1\u7814\u7a76\u306b\u3088\u308b\u3068\u3001\u4e2d\u5e74\u671f\u306b1\u65e53\u301c5\u676f\u306e\u30b3\u30fc\u30d2\u30fc\u3092\u98f2\u3093\u3067\u3044\u305f\u4eba\u306f\u3001\u9ad8\u9f62\u671f\u306b\u306a\u3063\u3066\u3082\u8a18\u61b6\u529b\u3084\u601d\u8003\u529b\u306a\u3069\u306e\u8a8d\u77e5\u6a5f\u80fd\u304c\u4fdd\u305f\u308c\u3066\u3044\u308b\u50be\u5411\u304c\u3042\u308b<\/strong>\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\n

\u3053\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u3068\u3057\u3066\u3001\u30ab\u30d5\u30a7\u30a4\u30f3\u306e\u795e\u7d4c\u4fdd\u8b77\u4f5c\u7528\u3084\u3001\u6297\u9178\u5316\u6210\u5206\u306e\u8133\u5185\u708e\u75c7\u6291\u5236\u52b9\u679c\u304c\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

CAIDE Study\uff08Eskelinen et al., 2009\uff09<\/a><\/p>\n

\u4e00\u6642\u7684\u306a\u6ce8\u610f\u529b\u30fb\u96c6\u4e2d\u529b\u30fb\u899a\u9192\u306e\u5411\u4e0a<\/h4>\n

Nehlig\uff082016\uff09\u203b1\u306b\u3088\u308b\u3068\u3001\u30ab\u30d5\u30a7\u30a4\u30f3\u306f\u8133\u5185\u306b\u3042\u308b\u300c\u30a2\u30c7\u30ce\u30b7\u30f3\u53d7\u5bb9\u4f53\u300d\u3068\u547c\u3070\u308c\u308b\u5834\u6240\u306b\u7d50\u3073\u3064\u304d\u3001\u30a2\u30c7\u30ce\u30b7\u30f3\u3068\u3044\u3046\u7720\u6c17\u3092\u5f15\u304d\u8d77\u3053\u3059\u7269\u8cea\u306e\u50cd\u304d\u3092\u30d6\u30ed\u30c3\u30af\u3059\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f\u3002
\u3053\u308c\u306b\u3088\u308a\u3001\u8133\u306e\u6d3b\u52d5\u304c\u6291\u5236\u3055\u308c\u306b\u304f\u304f\u306a\u308a\u3001\u4e2d\u67a2\u795e\u7d4c\u304c\u6d3b\u767a\u5316\u3059\u308b\u3053\u3068\u3067\u3001\u7720\u6c17\u306e\u8efd\u6e1b\u3084\u3001\u6ce8\u610f\u529b\u30fb\u53cd\u5fdc\u901f\u5ea6\u306e\u5411\u4e0a\u3068\u3044\u3063\u305f\u52b9\u679c\u304c\u5f97\u3089\u308c\u308b<\/strong>\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u203b\uff11 Nehlig A., Brain Research Reviews, 2016<\/a><\/p>\n

\u30b3\u30fc\u30d2\u30fc \u52b9\u679c \uff5c\u8840\u5727\u3078\u306e\u5f71\u97ff\u306f\u4e0a\u304c\u308b\uff1f\u4e0b\u304c\u308b\uff1f<\/h3>\n

\"\"<\/p>\n\n\n\n\n\n
\u9ad8\u8840\u5727\u30fb\u30ab\u30d5\u30a7\u30a4\u30f3\u975e\u8010\u6027\u8005<\/td>\n\u30ab\u30d5\u30a7\u30a4\u30f3\u6442\u53d630\u5206\u4ee5\u5185\u306b\u4e00\u6642\u7684\u306b\u4e0a\u6607\u3059\u308b<\/td>\n<\/tr>\n
\u30b3\u30fc\u30d2\u30fc\u3092\u6bce\u65e5\u98f2\u307f\u3001\u8010\u6027\u304c\u51fa\u6765\u3066\u3044\u308b\u4eba<\/td>\n\u5f71\u97ff\u307b\u307c\u306a\u3057<\/td>\n<\/tr>\n
\u30b3\u30fc\u30d2\u30fc\u306e\u7fd2\u6163\u95a2\u4fc2\u306a\u304f\u3001\u30ab\u30d5\u30a7\u30a4\u30f3\u30ec\u30b9\u30b3\u30fc\u30d2\u30fc<\/td>\n\u4e00\u6642\u7684\u306a\u4e0a\u6607\u306a\u3057<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u4e00\u6642\u7684\u306b\u8840\u5727\u3092\u4e0a\u6607\u3055\u305b\u308b\uff08\u7279\u306b\u30ab\u30d5\u30a7\u30a4\u30f3\u975e\u8010\u6027\u8005\uff09<\/h4>\n

\u30ab\u30d5\u30a7\u30a4\u30f3\u306f\u4ea4\u611f\u795e\u7d4c\u3092\u523a\u6fc0\u3057\u3001\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u306e\u5206\u6ccc\u3092\u4fc3\u9032\u3059\u308b\u305f\u3081\u3001\u6442\u53d630\u5206\u4ee5\u5185\u306b\u8840\u5727\u3092\u4e0a\u6607\u3055\u305b\u308b<\/strong>\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u7279\u306b\u30ab\u30d5\u30a7\u30a4\u30f3\u306b\u6163\u308c\u3066\u3044\u306a\u3044\u4eba\u3084\u8840\u5727\u304c\u9ad8\u3081\u306e\u4eba\u306f\u3001\u3053\u306e\u5f71\u97ff\u3092\u5f37\u304f\u53d7\u3051\u3084\u3059\u3044\u3067\u3059\u3002\u4e0a\u6607\u306f\u901a\u5e383\u301c4\u6642\u9593\u4ee5\u5185\u306b\u5143\u306b\u623b\u308a\u307e\u3059\u3002<\/p>\n

\uff08Mesas AE et al., Am J Clin Nutr, 2011\uff09<\/a><\/p>\n

\u6bce\u65e5\u98f2\u3080\u7fd2\u6163\u304c\u3042\u308b\u4eba\u3067\u306f\u3001\u8840\u5727\u3078\u306e\u5f71\u97ff\u306f\u307b\u307c\u306a\u304f\u306a\u308b<\/h4>\n

\u30b3\u30fc\u30d2\u30fc\u3092\u98f2\u3080\u7fd2\u6163\u306e\u3042\u308b\u4eba\u306f\u3001\u30ab\u30d5\u30a7\u30a4\u30f3\u306b\u3088\u308b\u8840\u5727\u306e\u4e0a\u6607\u306b\u5bfe\u3059\u308b\u8010\u6027\u304c\u5f62\u6210\u3055\u308c\u3001\u8840\u5727\u304c\u9ad8\u3081\u306b\u306a\u308b\u30ea\u30b9\u30af\u304c\u4e0a\u304c\u3089\u306a\u3044<\/strong>\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

Geleijnse JM (2008).<\/a><\/p>\n

\u30c7\u30ab\u30d5\u30a7\u30b3\u30fc\u30d2\u30fc\u3067\u306f\u8840\u5727\u3078\u306e\u5f71\u97ff\u306f\u307b\u3068\u3093\u3069\u306a\u3044<\/h4>\n

\u30c7\u30ab\u30d5\u30a7\uff08\u30ab\u30d5\u30a7\u30a4\u30f3\u9664\u53bb\u6e08\u307f\u30b3\u30fc\u30d2\u30fc\uff09\u306b\u306f\u8840\u5727\u3092\u4e0a\u3052\u308b\u30ab\u30d5\u30a7\u30a4\u30f3\u304c\u542b\u307e\u308c\u306a\u3044\u305f\u3081\u3001\u4e00\u6642\u7684\u306a\u8840\u5727\u4e0a\u6607\u4f5c\u7528\u306f\u898b\u3089\u308c\u307e\u305b\u3093\u3002<\/strong><\/p>\n

\u3080\u3057\u308d\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\uff08\u30af\u30ed\u30ed\u30b2\u30f3\u9178\u306a\u3069\uff09\u306b\u3088\u308b\u8840\u7ba1\u62e1\u5f35\u4f5c\u7528\u3084\u6297\u708e\u75c7\u52b9\u679c\u304c\u30d7\u30e9\u30b9\u306b\u50cd\u304f\u53ef\u80fd\u6027\u3082\u3042\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n

Alhabeeb et al. (2022)<\/a><\/p>\n

\u5faa\u74b0\u5668\u306e\u5065\u5eb7\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b<\/h4>\n

\u6bce\u65e53\u301c5\u676f\u307b\u3069\u306e\u30b3\u30fc\u30d2\u30fc\u3092\u98f2\u3080\u7fd2\u6163\u304c\u3042\u308b\u4eba\u306f\u3001\u5fc3\u81d3\u3084\u8840\u7ba1\u306e\u4e0d\u8abf\u306e\u30ea\u30b9\u30af\u304c\u7d0415\uff05\u6e1b\u5c11\u3059\u308b<\/strong>\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u3053\u306e\u52b9\u679c\u306e\u80cc\u666f\u306b\u306f\u3001\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u3067\u3042\u308b\u30af\u30ed\u30ed\u30b2\u30f3\u9178\u306b\u3088\u308b\u6297\u9178\u5316\u30fb\u6297\u708e\u75c7\u30fb\u8840\u7ba1\u4fdd\u8b77\u4f5c\u7528\u304c\u6319\u3052\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

American Journal of Agricultural and Food Chemistry\uff082017\uff09<\/a><\/p>\n

\u30b3\u30fc\u30d2\u30fc \u52b9\u679c \uff5c\u808c\u8352\u308c\u3084\u7f8e\u808c\u3078\u306e\u5f71\u97ff\u306f\uff1f<\/h3>\n

\"\"<\/p>\n

\u6297\u9178\u5316\u4f5c\u7528\u306b\u3088\u308a\u3001\u30b7\u30df\u30fb\u3057\u308f\u30fb\u304f\u3059\u307f\u306a\u3069\u306e\u808c\u8001\u5316\u3092\u6291\u3048\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b<\/h4>\n

\u30b3\u30fc\u30d2\u30fc\u306b\u306f\u3001\u300c\u30af\u30ed\u30ed\u30b2\u30f3\u9178\u300d\u3084\u300c\u30e1\u30e9\u30ce\u30a4\u30b8\u30f3\u300d\u3068\u3044\u3063\u305f\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u304c\u591a\u304f\u542b\u307e\u308c\u3066\u304a\u308a\u3001\u3053\u308c\u3089\u306b\u306f\u4f53\u3092\u30b5\u30d3\u3064\u304d\u304b\u3089\u5b88\u308b\u5f37\u3044\u6297\u9178\u5316\u4f5c\u7528\u304c\u3042\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u7d2b\u5916\u7dda\u3084\u30b9\u30c8\u30ec\u30b9\u306b\u3088\u308b\u6d3b\u6027\u9178\u7d20\u30c0\u30e1\u30fc\u30b8\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u304c\u3001\u808c\u306e\u30b3\u30e9\u30fc\u30b2\u30f3\u91cf\u306e\u7dad\u6301\u3084\u8272\u7d20\u6c88\u7740\u306e\u6291\u6b62\u3001\u5f3e\u529b\u30fb\u900f\u660e\u611f\u306e\u4fdd\u6301\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b<\/strong>\u3068\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

Rodrigues et\u202fal.\uff082023, Cosmetics\uff09<\/a><\/p>\n

\u8d64\u3089\u9854\uff08\u30ed\u30b6\u30b1\u30a2\uff09\u306e\u8efd\u6e1b\u52b9\u679c\u304c\u3042\u308b<\/h4>\n

1\u65e5\u3042\u305f\u308a\u30b3\u30fc\u30d2\u30fc\u30924\u676f\u4ee5\u4e0a\u98f2\u3080\u4eba\u306f\u3001\u4ed6\u306e\u98f2\u6599\u3092\u98f2\u3080\u4eba\u3068\u6bd4\u3079\u3066\u8d64\u3089\u9854\uff08\u30ed\u30b6\u30b1\u30a2\uff09\u306e\u767a\u75c7\u30ea\u30b9\u30af\u304c\u660e\u3089\u304b\u306b\u4f4e\u3044<\/strong>\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u306e\u52b9\u679c\u306f\u3001\u30b3\u30fc\u30d2\u30fc\u306e\u6e29\u5ea6\u3067\u306f\u306a\u304f\u3001\u30ab\u30d5\u30a7\u30a4\u30f3\u81ea\u4f53\u304c\u8840\u7ba1\u3092\u53ce\u7e2e\u3055\u305b\u308b\u4f5c\u7528\u306b\u95a2\u4fc2\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u8840\u7ba1\u306e\u62e1\u5f35\u306b\u3088\u308b\u8d64\u307f\u3092\u6291\u3048\u308b\u3053\u3068\u3067\u3001\u9854\u306e\u8d64\u3089\u307f\u304c\u51fa\u306b\u304f\u304f\u306a\u308b\u3068\u3044\u3046\u4ed5\u7d44\u307f\u3067\u3059\u3002<\/p>\n

Association of Caffeine Intake and Caffeinated Coffee Consumption With Risk of Incident Rosacea in Women\uff08Li\u202fet\u202fal., JAMA Dermatology<\/em>, 2018\uff09<\/span><\/a><\/p>\n

\u8840\u6d41\u4fc3\u9032\u306b\u3088\u308a\u3001\u8840\u8272\u611f\u3068\u30c4\u30e4\u808c\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b<\/h4>\n

\u5b9f\u969b\u306b\u3001\u30ab\u30d5\u30a7\u30a4\u30f3\u3092\u6442\u53d6\u3059\u308b\u3068\u3001\u76ae\u819a\u306e\u5fae\u5c0f\u8840\u7ba1\u304c\u523a\u6fc0\u306b\u3057\u3063\u304b\u308a\u53cd\u5fdc\u3057\u3001\u8840\u6d41\u304c\u30b9\u30e0\u30fc\u30ba\u306b\u306a\u308b\u3068\u3044\u3046\u7814\u7a76\u7d50\u679c\u3082\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u3053\u308c\u306b\u3088\u308a\u3001\u9178\u7d20\u3084\u6804\u990a\u304c\u808c\u306b\u884c\u304d\u6e21\u308a\u3084\u3059\u304f\u306a\u308a\u3001\u8840\u8272\u611f\u3084\u30c4\u30e4\u306e\u3042\u308b\u5065\u5eb7\u7684\u306a\u808c\u306e\u7dad\u6301\u306b\u5f79\u7acb\u3064<\/strong>\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

Noguchi et al., 2015, J Pharmacol Sci<\/a><\/p>\n

\u808c\u30c8\u30e9\u30d6\u30eb\u306e\u539f\u56e0\u306b\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b<\/h4>\n

\u30ab\u30d5\u30a7\u30a4\u30f3\u3092\u6442\u308b\u3053\u3068\u3067\u3001\u30b9\u30c8\u30ec\u30b9\u30db\u30eb\u30e2\u30f3\u3067\u3042\u308b\u201c\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u201d\u304c\u5897\u52a0\u3057\u3084\u3059\u304f\u306a\u308b\u3053\u3068\u304c\u81e8\u5e8a\u8a66\u9a13\u3067\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u3053\u306e\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u306f\u76ae\u8102\u817a\u3092\u523a\u6fc0\u3057\u3001\u76ae\u8102\u306e\u5206\u6ccc\u3092\u6d3b\u767a\u306b\u3059\u308b\u305f\u3081\u3001\u30cb\u30ad\u30d3\u3084\u808c\u30c8\u30e9\u30d6\u30eb\u306e\u539f\u56e0\u306b\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/strong><\/p>\n

Lovallo et al., 2005<\/a><\/p>\n

Evaluation of Hormonal Factors in Acne Vulgaris and the Course of Acne Vulgaris Treatment with Contraceptive-Based Therapies in Young Adult Women<\/a><\/p>\n

\u30b3\u30fc\u30d2\u30fc \u52b9\u679c\uff5c\u30c0\u30a4\u30a8\u30c3\u30c8\u00a0 \u8102\u80aa\u71c3\u713c\u3084\u4ee3\u8b1d\u4fc3\u9032\u306e\u4ed5\u7d44\u307f<\/h3>\n

\"\"<\/h4>\n

\u30ab\u30d5\u30a7\u30a4\u30f3\u304c\u8102\u80aa\u5206\u89e3\uff08\u30ea\u30dd\u30ea\u30b7\u30b9\uff09\u3092\u4fc3\u9032\u3059\u308b<\/h4>\n

Acheson\u3089\uff081980\u5e74\uff09\u306e\u81e8\u5e8a\u8a66\u9a13\u3067\u306f\u3001\u30ab\u30d5\u30a7\u30a4\u30f3\u3092\u6442\u53d6\u3059\u308b\u3068\u8840\u6db2\u4e2d\u306e\u8102\u80aa\u9178\u6fc3\u5ea6\u304c\u4e0a\u6607\u3057\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u304c\u9ad8\u307e\u308a\u3001\u8102\u80aa\u306e\u71c3\u713c\uff08\uff1d\u30ea\u30dd\u30ea\u30b7\u30b9\uff09\u304c\u4fc3\u9032\u3055\u308c\u308b<\/strong>\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

\u3053\u308c\u306f\u3001\u30ab\u30d5\u30a7\u30a4\u30f3\u306e\u4f5c\u7528\u3067\u4ea4\u611f\u795e\u7d4c\u304c\u523a\u6fc0\u3055\u308c\u3001\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u3084\u30a8\u30d4\u30cd\u30d5\u30ea\u30f3\u306e\u5206\u6ccc\u304c\u5897\u3048\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u03b2\u2011\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u53d7\u5bb9\u4f53\u304c\u6d3b\u6027\u5316\u3055\u308c\u308b\u305f\u3081\u3067\u3059\u3002<\/p>\n

\u305d\u306e\u7d50\u679c\u3001\u30db\u30eb\u30e2\u30f3\u611f\u53d7\u6027\u30ea\u30d1\u30fc\u30bc\uff08HSL\uff09\u304c\u50cd\u304d\u3001\u8102\u80aa\u7d30\u80de\u304b\u3089\u8102\u80aa\u9178\u304c\u8840\u6db2\u4e2d\u306b\u653e\u51fa\u3055\u308c\u308b\u4ed5\u7d44\u307f\u3067\u3059\u3002<\/p>\n

\u8102\u80aa\u9178\u306f\u3001\u904b\u52d5\u3084\u6d3b\u52d5\u306b\u3088\u3063\u3066\u30a8\u30cd\u30eb\u30ae\u30fc\u6e90\u3068\u3057\u3066\u5229\u7528\u3055\u308c\u3084\u3059\u304f\u306a\u308b\u305f\u3081\u3001\u904b\u52d5\u524d30\u301c60\u5206\u524d\u306e\u30b3\u30fc\u30d2\u30fc\u6442\u53d6\u304c\u8102\u80aa\u306e\u71c3\u713c\u306b\u52b9\u679c\u7684\u3068\u3055\u308c\u307e\u3059\u3002<\/p>\n

Caffeine and coffee: their influence on metabolic rate and substrate utilization in normal weight and obese individuals\uff08Acheson et\u202fal., Am J Clin Nutr<\/em>, 1980\uff09<\/a><\/p>\n

 <\/p>\n

\u5c02\u9580\u7528\u8a9e\u306e\u89e3\u8aac<\/p>\n\n\n\n\n\n\n
\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3<\/p>\n

\uff08norepinephrine\uff09<\/td>\n

\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u306f\u3001\u4ea4\u611f\u795e\u7d4c\u304b\u3089\u5206\u6ccc\u3055\u308c\u308b\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u306e\u3072\u3068\u3064\u3067\u3001\u30b9\u30c8\u30ec\u30b9\u3084\u7dca\u5f35\u6642\u306b\u5206\u6ccc\u304c\u5897\u52a0\u3057\u307e\u3059\u3002<\/p>\n

\u8840\u7ba1\u3092\u53ce\u7e2e\u3055\u305b\u3066\u8840\u5727\u3092\u4e0a\u3052\u305f\u308a\u3001\u5fc3\u62cd\u6570\u3092\u4e0a\u3052\u305f\u308a\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u3092\u4fc3\u9032\u3059\u308b\u306a\u3069\u3001\u300c\u6226\u3046\u304b\u9003\u3052\u308b\u304b\u300d\u306e\u53cd\u5fdc\uff08\u95d8\u4e89\u30fb\u9003\u8d70\u53cd\u5fdc\uff09\u306b\u95a2\u4e0e\u3057\u307e\u3059\u3002<\/td>\n<\/tr>\n

\u30a8\u30d4\u30cd\u30d5\u30ea\u30f3<\/p>\n

\uff08epinephrine, \u901a\u79f0\uff1a\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\uff09<\/td>\n

\u30a8\u30d4\u30cd\u30d5\u30ea\u30f3\u306f\u526f\u814e\u9ac4\u8cea\u304b\u3089\u5206\u6ccc\u3055\u308c\u308b\u30db\u30eb\u30e2\u30f3\u3067\u3001\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u3068\u4f3c\u305f\u50cd\u304d\u3092\u6301\u3061\u307e\u3059\u3002<\/p>\n

\u904b\u52d5\u3084\u30b9\u30c8\u30ec\u30b9\u6642\u306b\u5206\u6ccc\u3055\u308c\u3001\u5fc3\u62cd\u6570\u306e\u5897\u52a0\u3001\u8840\u7cd6\u5024\u306e\u4e0a\u6607\u3001\u8102\u80aa\u5206\u89e3\u306e\u4fc3\u9032\u306a\u3069\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u3002\u8102\u80aa\u71c3\u713c\u306e\u4fc3\u9032\u306b\u3082\u95a2\u308f\u308b\u91cd\u8981\u306a\u7269\u8cea\u3067\u3059\u3002<\/td>\n<\/tr>\n

\u03b2\u2011\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u53d7\u5bb9\u4f53<\/p>\n

\uff08\u03b2-adrenergic receptor\uff09<\/td>\n

\u3053\u308c\u306f\u3001\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u3084\u30a8\u30d4\u30cd\u30d5\u30ea\u30f3\u304c\u4f5c\u7528\u3059\u308b\u300c\u53d7\u5bb9\u4f53\uff08\u30bb\u30f3\u30b5\u30fc\uff09\u300d\u3067\u3059\u3002<\/p>\n

\u4f53\u306e\u3055\u307e\u3056\u307e\u306a\u7d44\u7e54\uff08\u5fc3\u81d3\u3001\u8102\u80aa\u7d30\u80de\u3001\u7b4b\u8089\u306a\u3069\uff09\u306b\u5b58\u5728\u3057\u3001\u3053\u308c\u304c\u6d3b\u6027\u5316\u3055\u308c\u308b\u3068\uff1a\u5fc3\u81d3\u3067\u306f\u5fc3\u62cd\u304c\u5897\u3048\u308b\u30fb\u8102\u80aa\u7d30\u80de\u3067\u306f\u30db\u30eb\u30e2\u30f3\u611f\u53d7\u6027\u30ea\u30d1\u30fc\u30bc\u304c\u50cd\u304d\u3001\u8102\u80aa\u3092\u5206\u89e3\uff08\uff1d\u30ea\u30dd\u30ea\u30b7\u30b9\uff09\u3068\u3044\u3063\u305f\u751f\u7406\u53cd\u5fdc\u304c\u8d77\u3053\u308a\u307e\u3059\u3002<\/td>\n<\/tr>\n

\u30db\u30eb\u30e2\u30f3\u611f\u53d7\u6027\u30ea\u30d1\u30fc\u30bc<\/p>\n

\uff08Hormone-Sensitive Lipase\uff1aHSL\uff09<\/td>\n

\u8102\u80aa\u7d30\u80de\u306b\u84c4\u3048\u3089\u308c\u305f\u4e2d\u6027\u8102\u80aa\u3092\u5206\u89e3\u3057\u3066\u8102\u80aa\u9178\u3068\u30b0\u30ea\u30bb\u30ed\u30fc\u30eb\u3092\u53d6\u308a\u51fa\u3059\u9175\u7d20\u3067\u3059\u3002<\/p>\n

\u8102\u80aa\u71c3\u713c\uff08\u30ea\u30dd\u30ea\u30b7\u30b9\uff09\u306e\u201c\u30b9\u30a4\u30c3\u30c1\u201d\u306e\u3088\u3046\u306a\u5b58\u5728\u3067\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u304c\u5fc5\u8981\u306a\u3068\u304d\u306b\u6d3b\u6027\u5316\u3055\u308c\u307e\u3059\u3002<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u57fa\u790e\u4ee3\u8b1d\u7387\u3092\u4e00\u6642\u7684\u306b\u4e0a\u6607\u3055\u305b\u308b<\/span><\/h4>\n

Dulloo\u3089\uff081989\u5e74\uff09\u306e\u7814\u7a76\u3067\u306f\u3001\u30ab\u30d5\u30a7\u30a4\u30f3\u6442\u53d6\u306b\u3088\u3063\u3066\u5b89\u9759\u6642\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u6d88\u8cbb\u91cf\uff08REE\uff09\u304c\u4e00\u56de\u306e\u6442\u53d6\u3067\u7d043\uff5e4%\u3001<\/strong>\u4e00\u65e5\u3092\u901a\u3058\u3066\u6700\u592711%\u307e\u3067\u5897\u52a0\u3057\u3001\u3053\u306e\u5897\u52a0\u52b9\u679c\u306f\u6442\u53d6\u5f8c\u7d042.5\u6642\u9593\u7d9a\u304f<\/strong>\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

\u7fd2\u6163\u7684\u306b\u30ab\u30d5\u30a7\u30a4\u30f3\u3092\u6442\u3063\u3066\u3044\u308b\u4eba\u3067\u3082\u3001\u52b9\u679c\u304c\u5b8c\u5168\u306b\u6d88\u3048\u308b\u308f\u3051\u3067\u306f\u306a\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\uff08Dulloo et al., American Journal of Clinical Nutrition, 1989\uff09<\/a><\/p>\n

\u30af\u30ed\u30ed\u30b2\u30f3\u9178\u304c\u8102\u80aa\u306e\u84c4\u7a4d\u3092\u6291\u3048\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b<\/h4>\n

\u30b3\u30fc\u30d2\u30fc\u306b\u542b\u307e\u308c\u308b\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u306e\u4e00\u7a2e\u300c\u30af\u30ed\u30ed\u30b2\u30f3\u9178\u300d\u306f\u3001\u809d\u81d3\u3067\u306e\u8102\u80aa\u5408\u6210\u3092\u6291\u3048\u308b\u3068\u3068\u3082\u306b\u3001<\/strong>\u30a8\u30cd\u30eb\u30ae\u30fc\u3068\u3057\u3066\u4f7f\u308f\u308c\u308b\u8102\u80aa\u9178\u306e\u71c3\u713c\u304c\u4fc3\u9032\u3055\u308c\u308b\u4f5c\u7528\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/strong><\/p>\n

\u3053\u306e\u305f\u3081\u3001\u98df\u5f8c\u306e\u8840\u7cd6\u5024\u3068\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u4e0a\u6607\u304c\u7de9\u3084\u304b\u306b\u306a\u308b\u3068\u3068\u3082\u306b\u3001\u5185\u81d3\u8102\u80aa\u306e\u84c4\u7a4d\u3092\u4e88\u9632\u3059\u308b\u52b9\u679c\u3082\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\uff08Roles of Chlorogenic Acid on Regulating Glucose and Lipids, PMC 2013\uff09<\/a><\/p>\n

\uff08Potential of Chlorogenic Acid in the Management of Metabolic Dysfunction\u2011Associated Steatotic Liver Disease, MDPI 2024<\/a><\/p>\n

\u7a7a\u8179\u6642\u306e\u6442\u53d6\u3084\u98f2\u307f\u3059\u304e\u306f\u9006\u52b9\u679c\u306b\u306a\u308b\u3053\u3068\u3082\u3042\u308b<\/span><\/h4>\n

\u7a7a\u8179\u306e\u72b6\u614b\u3067\u5927\u91cf\u306e\u30ab\u30d5\u30a7\u30a4\u30f3\u3092\u6442\u53d6\u3059\u308b\u3068\u3001\u30b9\u30c8\u30ec\u30b9\u30db\u30eb\u30e2\u30f3\u300c\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u300d\u304c\u904e\u5270\u306b\u5206\u6ccc\u3055\u308c\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n

\u3053\u306e\u30db\u30eb\u30e2\u30f3\u304c\u5897\u3048\u3059\u304e\u308b\u3068\u3001\u8102\u80aa\u5206\u89e3\u3092\u6291\u3048\u308b\u30db\u30eb\u30e2\u30f3\u3067\u3042\u308b\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u52b9\u304d\u304c\u60aa\u304f\u306a\u308b\uff08\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\uff09\u3053\u3068\u3084\u5185\u81d3\u8102\u80aa\u306e\u84c4\u7a4d\u306b\u3064\u306a\u304c\u308b\u30ea\u30b9\u30af\u304c\u3042\u308b\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u307e\u305f\u3001\u30ab\u30d5\u30a7\u30e9\u30c6\u3084\u30d5\u30e9\u30da\u30c1\u30fc\u30ce\u3001\u7f36\u30b3\u30fc\u30d2\u30fc\u306a\u3069\u306b\u591a\u304f\u542b\u307e\u308c\u308b\u7802\u7cd6\u3084\u30df\u30eb\u30af\u306f\u3001\u98f2\u307f\u3059\u304e\u308b\u3068\u4f59\u5206\u306a\u30ab\u30ed\u30ea\u30fc\u3092\u53d6\u308a\u3059\u304e\u3066\u3057\u307e\u3046\u539f\u56e0\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n

\u7d50\u679c\u3068\u3057\u3066\u3001\u4f53\u8102\u80aa\u306e\u5897\u52a0\u306b\u3064\u306a\u304c\u308b\u3053\u3068\u3082\u3002\u305d\u306e\u305f\u3081\u3001\u300c\u30d6\u30e9\u30c3\u30af\u3067\u3001\u98df\u5f8c\u3084\u904b\u52d5\u524d\u306b\u98f2\u3080\u300d<\/strong>\u304c\u304a\u3059\u3059\u3081\u3067\u3059\u3002<\/p>\n

Lovallo et al., 2005<\/a><\/p>\n

\u30b3\u30fc\u30d2\u30fc\u00a0\u52b9\u679c\uff5c\u30c7\u30e1\u30ea\u30c3\u30c8\u00a0 \u98f2\u307f\u904e\u304e\u3084\u30ab\u30d5\u30a7\u30a4\u30f3\u306e\u6ce8\u610f\u70b9<\/h3>\n

\"\"<\/p>\n

\u30ab\u30d5\u30a7\u30a4\u30f3\u306e\u904e\u5270\u6442\u53d6\u306f\u4e0d\u7720\u30fb\u52d5\u60b8\u30fb\u4e0d\u5b89\u611f\u3092\u5f15\u304d\u8d77\u3053\u3059<\/h4>\n

\u8907\u6570\u306e\u7814\u7a76\u306b\u3088\u308b\u3068\u3001\u30ab\u30d5\u30a7\u30a4\u30f3\u6442\u53d6\u306b\u3088\u308a\u7761\u7720\u6f5c\u6642\u306e\u5ef6\u9577\u3001\u7dcf\u7761\u7720\u6642\u9593\u306e\u6e1b\u5c11\u3001\u7761\u7720\u52b9\u7387\u306e\u4f4e\u4e0b\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/strong><\/p>\n

\u307e\u305f\u3001\u30ab\u30d5\u30a7\u30a4\u30f3\u306b\u306f\u5fc3\u62cd\u6570\u3084\u8840\u5727\u3092\u4e0a\u3052\u308b\u4f5c\u7528\u304c\u3042\u308a\u3001\u3068\u304f\u306b\u5348\u5f8c\u4ee5\u964d\u306e\u6442\u53d6\u306f\u4e0d\u7720\u3092\u62db\u304d\u3084\u3059\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u4e00\u822c\u7684\u306b1\u65e5\u3042\u305f\u308a400mg\uff08\u30b3\u30fc\u30d2\u30fc\u7d043\uff5e4\u676f\uff09\u3092\u4e0a\u9650\u3068\u3057\u3001\u3053\u308c\u3092\u8d85\u3048\u308b\u3068\u5fc3\u62cd\u6570\u306e\u5897\u52a0\u3084\u7761\u7720\u969c\u5bb3\u306a\u3069\u306e\u526f\u4f5c\u7528\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308a\u307e\u3059\u3002<\/p>\n

Caffeine Effects on Sleep Taken 0, 3, or 6 Hours before Going to Bed,2013<\/a><\/p>\n

Coffee acutely increases sympathetic nerve activity and blood pressure in nonhabitual coffee drinkers\u201d\uff08Circulation<\/em>, 2000\uff09<\/a><\/p>\n

\u80c3\u9178\u5206\u6ccc\u306e\u4fc3\u9032\u306b\u3088\u308a\u3001\u80c3\u3082\u305f\u308c\u30fb\u80c3\u75db\u30fb\u80c3\u708e\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308b<\/h4>\n

\u30b3\u30fc\u30d2\u30fc\uff08\u7279\u306b\u7a7a\u8179\u6642\u306e\u6442\u53d6\uff09\u306f\u80c3\u9178\u5206\u6ccc\u3092\u523a\u6fc0\u3057\u3001\u80c3\u7c98\u819c\u3078\u306e\u523a\u6fc0\u304c\u5f37\u307e\u308a\u3001\u80c3\u75db\u3084\u80f8\u3084\u3051\u306e\u60aa\u5316\u306b\u3064\u306a\u304c\u308b\u53ef\u80fd\u6027<\/strong>\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u98df\u5f8c\u306b\u98f2\u3093\u3060\u308a\u3001\u30df\u30eb\u30af\u3084\u30af\u30ea\u30fc\u30e0\u3092\u52a0\u3048\u3066\u98f2\u3093\u3060\u308a\u3059\u308b\u3053\u3068\u3067\u3001\u80c3\u3078\u306e\u523a\u6fc0\u3092\u548c\u3089\u3052\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n

Effects of Coffee on the Gastro\u2011Intestinal Tract: A Narrative Review\uff08Nutrients, 2022\uff09<\/a><\/p>\n

\u9244\u5206\u3084\u30ab\u30eb\u30b7\u30a6\u30e0\u306a\u3069\u306e\u30df\u30cd\u30e9\u30eb\u5438\u53ce\u3092\u963b\u5bb3\u3059\u308b<\/h4>\n

\u30b3\u30fc\u30d2\u30fc\u306b\u542b\u307e\u308c\u308b\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u985e\uff08\u7279\u306b\u30af\u30ed\u30ed\u30b2\u30f3\u9178\u3084\u30bf\u30f3\u30cb\u30f3\uff09\u306f\u3001\u98df\u4e8b\u306b\u542b\u307e\u308c\u308b\u300c\u975e\u30d8\u30e0\u9244\uff08\u690d\u7269\u6027\u98df\u54c1\u306b\u591a\u3044\u9244\uff09\u300d\u3068\u7d50\u3073\u3064\u3044\u3066\u3001\u5438\u53ce\u3055\u308c\u306b\u304f\u3044\u5f62\u306b\u5909\u3048\u3066\u3057\u307e\u3046\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u9244\u6b20\u4e4f\u3084\u8ca7\u8840\u6c17\u5473\u306e\u4eba\u304c\u98df\u4e8b\u4e2d\u3084\u98df\u5f8c\u3059\u3050\u306b\u30b3\u30fc\u30d2\u30fc\u3092\u98f2\u3080\u3068\u3001\u9244\u306e\u5438\u53ce\u304c\u59a8\u3052\u3089\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b<\/strong>\u3068\u8a00\u308f\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u307e\u305f\u3001\u30b3\u30fc\u30d2\u30fc\u306b\u542b\u307e\u308c\u308b\u30ab\u30d5\u30a7\u30a4\u30f3\u306b\u306f\u5229\u5c3f\u4f5c\u7528\u304c\u3042\u308a\u3001\u4f53\u5185\u306e\u30ab\u30eb\u30b7\u30a6\u30e0\u304c\u5c3f\u3068\u3057\u3066\u6392\u51fa\u3055\u308c\u3084\u3059\u304f\u306a\u308b\u3053\u3068\u3082\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u3046\u3057\u305f\u4f5c\u7528\u304c\u7d9a\u304f\u3068\u3001\u9577\u671f\u7684\u306b\u306f\u9aa8\u5bc6\u5ea6\u306e\u4f4e\u4e0b\u306b\u3064\u306a\u304c\u308b\u30ea\u30b9\u30af\u3082\u6307\u6458\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u7279\u306b\u9244\u3084\u30ab\u30eb\u30b7\u30a6\u30e0\u304c\u4e0d\u8db3\u3057\u304c\u3061\u306a\u5973\u6027\u3084\u9ad8\u9f62\u8005\u3001\u9589\u7d4c\u5f8c\u306e\u65b9\u306b\u3068\u3063\u3066\u306f\u3001\u30b3\u30fc\u30d2\u30fc\u306e\u98f2\u307f\u65b9\u3084\u30bf\u30a4\u30df\u30f3\u30b0\u306b\u5c11\u3057\u6ce8\u610f\u3092\u6255\u3046\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/p>\n

Hurrell RF et al. (1999)\u201cInhibition of non\u2011haem iron absorption in man by polyphenolic\u2011containing beverages.\u201d<\/a><\/p>\n

Disler et al. (1975)\u201cThe effect of tea on iron absorption.\u201dGut, 16(3), 193\u2013200.<\/a><\/p>\n

Heaney RP et al. (1982)\u201cEffects of caffeine on bone and the calcium economy.\u201d<\/a><\/p>\n

Barrett\u2011Connor E et al. (1994)\u201cCoffee\u2011Associated Osteoporosis Offset by Daily Milk Consumption. The Rancho Bernardo Study.\u201d<\/a><\/p>\n

\u982d\u75db\u30fb\u96e2\u8131\u75c7\u72b6\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u3042\u308b<\/h4>\n

\u30ab\u30d5\u30a7\u30a4\u30f3\u4f9d\u5b58\u304c\u5f62\u6210\u3055\u308c\u308b\u3068\u3001\u30b3\u30fc\u30d2\u30fc\u306e\u98f2\u7528\u3092\u6025\u306b\u3084\u3081\u305f\u969b\u306b\u3001\u982d\u75db\u30fb\u75b2\u52b4\u611f\u30fb\u96c6\u4e2d\u529b\u4f4e\u4e0b\u306a\u3069\u306e\u96e2\u8131\u75c7\u72b6\u304c\u73fe\u308c\u308b<\/strong>\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u6bce\u65e53\u676f\u4ee5\u4e0a\u98f2\u3093\u3067\u3044\u308b\u4eba\u304c\u7a81\u7136\u3084\u3081\u308b\u3068\u30012\u301c3\u65e5\u4ee5\u5185\u306b\u982d\u75db\u3084\u30a4\u30e9\u30a4\u30e9\u304c\u51fa\u3084\u3059\u3044\u305f\u3081\u3001\u6e1b\u91cf\u306f\u5f90\u3005\u306b\u884c\u3046\u306e\u304c\u7406\u60f3\u3067\u3059\u3002<\/p>\n

\uff08Juliano LM, Griffiths RR., Psychopharmacology, 2004\uff09<\/a><\/p>\n

\u52b9\u679c\u3092\u9ad8\u3081\u308b\u30b3\u30fc\u30d2\u30fc\u306e\u98f2\u307f\u65b9<\/h2>\n

\u52b9\u679c\u304c\u51fa\u308b\u307e\u3067\u306e\u6642\u9593\u3068\u6301\u7d9a\u6642\u9593\u306f\uff1f<\/h3>\n

\"\"<\/h3>\n

\u30ab\u30d5\u30a7\u30a4\u30f3\u306e\u52b9\u679c\u306f\u6442\u53d6\u5f8c30\u301c60\u5206\u3067\u6700\u5927\u306b\u306a\u308b<\/span><\/h4>\n

\u30ab\u30d5\u30a7\u30a4\u30f3\u306f\u5c0f\u8178\u304b\u3089\u7d20\u65e9\u304f\u5438\u53ce\u3055\u308c\u3001\u6442\u53d630\u301c60\u5206\u5f8c\u306b\u6700\u3082\u9ad8\u3044\u899a\u9192\u30fb\u96c6\u4e2d\u529b\u5411\u4e0a\u52b9\u679c\u304c\u5f97\u3089\u308c\u308b<\/strong>\u3068\u7814\u7a76\u3067\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u7279\u306b\u3001\u671d\u98df\u5f8c\u3084\u663c\u98df\u5f8c\u306e\u6442\u53d6\u30bf\u30a4\u30df\u30f3\u30b0\u306f\u3001\u3053\u306e\u30d4\u30fc\u30af\u52b9\u679c\u3068\u91cd\u306a\u308b\u305f\u3081\u3001\u4ed5\u4e8b\u3084\u52c9\u5f37\u3078\u306e\u96c6\u4e2d\u529b\u3092\u6700\u5927\u9650\u306b\u5f15\u304d\u51fa\u3059\u30bf\u30a4\u30df\u30f3\u30b0\u3068\u3057\u3066\u63a8\u5968\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\uff08Lorist & Snel, 2008; Van Soeren et al., 2004\uff09<\/a><\/p>\n

\u899a\u9192\u30fb\u96c6\u4e2d\u529b\u306e\u52b9\u679c\u306f\u7d043\u301c6\u6642\u9593\u6301\u7d9a\u3059\u308b<\/h4>\n

\u30ab\u30d5\u30a7\u30a4\u30f3\u306f\u5065\u5eb7\u306a\u6210\u4eba\u3067\u306f\u4f53\u5185\u3067\u534a\u5206\u306b\u5206\u89e3\u3055\u308c\u308b\u307e\u3067\uff08\u8840\u4e2d\u534a\u6e1b\u671f\uff09\u306b\u7d044\uff5e6\u6642\u9593\u304b\u304b\u308a\u3001\u3053\u308c\u306b\u4f34\u3046\u899a\u9192\u4f5c\u7528\u3084\u96c6\u4e2d\u529b\u5411\u4e0a\u3082\u6442\u53d6\u5f8c\u7d043\u301c6\u6642\u9593\u7d9a\u304f<\/strong>\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u5915\u65b9\u4ee5\u964d\u306b\u30b3\u30fc\u30d2\u30fc\u3092\u98f2\u3080\u3068\u3001\u5c31\u5bdd\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u304f\u306a\u308b\u305f\u3081\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n

A review of caffeine\u2019s effects on cognitive, physical and occupational performance<\/a><\/p>\n

\u8102\u80aa\u71c3\u713c\u30fb\u4ee3\u8b1d\u4fc3\u9032\u306e\u52b9\u679c\u306f\u6442\u53d6\u5f8c\u7d041\u6642\u9593\u304b\u3089\u59cb\u307e\u308a\u30013\u301c4\u6642\u9593\u7d9a\u304f<\/h4>\n

\u30ab\u30d5\u30a7\u30a4\u30f3\u6442\u53d6\u5f8c\u3001\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u5206\u6ccc\u304c\u5897\u52a0\u3057\u3001\u8102\u80aa\u5206\u89e3\uff08\u30ea\u30dd\u30ea\u30b7\u30b9\uff09\u3084\u57fa\u790e\u4ee3\u8b1d\u306e\u4e0a\u6607\u304c1\u6642\u9593\u4ee5\u5185\u306b\u59cb\u307e\u308a\u3001\u7d043\u301c4\u6642\u9593\u6301\u7d9a\u3059\u308b<\/strong>\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u904b\u52d5\u306e30\u301c60\u5206\u524d\u306b\u98f2\u3080\u3053\u3068\u3067\u3001\u8102\u80aa\u71c3\u713c\u52b9\u7387\u3092\u9ad8\u3081\u3089\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

Metabolic effects of caffeine in humans: lipid oxidation or futile cycling?<\/a><\/p>\n

\u5229\u5c3f\u4f5c\u7528\u3084\u80c3\u8178\u3078\u306e\u5f71\u97ff\u3082\u6442\u53d6\u5f8c1\u6642\u9593\u4ee5\u5185\u306b\u73fe\u308c\u308b<\/h4>\n

Neuhauser\u2011Berthold\u3089\uff081997\uff09\u306e\u7814\u7a76\u3067\u306f\u3001\u30b3\u30fc\u30d2\u30fc\u3092\u98f2\u3080\u4eba\u306f\u98f2\u7528\u5f8c\u306b\u5c3f\u91cf\u304c\u5897\u3048\u308b\u50be\u5411\u304c\u3042\u308a\u3001\u3053\u308c\u306f\u5229\u5c3f\u4f5c\u7528\u306b\u8d77\u56e0\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059<\/strong>\u3002<\/p>\n

\u4e00\u65b9\u3001Cohen & Booth\uff081975\uff09\u306f\u30ab\u30d5\u30a7\u30a4\u30f3\u304c\u80c3\u9178\u5206\u6ccc\u3092\u4fc3\u9032\u3057\u3001\u80c3\u3084\u8178\u306e\u6d3b\u52d5\u3092\u6d3b\u767a\u306b\u3059\u308b\u3053\u3068\u3092\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u4f1a\u8b70\u3084\u9577\u6642\u9593\u306e\u79fb\u52d5\u306e\u524d\u306b\u30b3\u30fc\u30d2\u30fc\u3092\u98f2\u3080\u5834\u5408\u3001\u3053\u308c\u3089\u306e\u5f71\u97ff\u3092\u8e0f\u307e\u3048\u3066\u30bf\u30a4\u30df\u30f3\u30b0\u3092\u8abf\u6574\u3059\u308b\u306e\u304c\u671b\u307e\u3057\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

Coffee Consumption and Total Body Water Homeostasis as Measured by Fluid Balance and Bioelectrical Impedance Analysis<\/a><\/p>\n

Gastric acid secretion and lower-esophageal-sphincter pressure in response to coffee and caffeine<\/a><\/p>\n

\u30b3\u30fc\u30d2\u30fc \u52b9\u679c \uff5c\u7a7a\u8179\u6642\u30fb\u98df\u5f8c\u3069\u3061\u3089\u304c\u826f\u3044\uff1f<\/h3>\n

\"\"<\/h3>\n

\u98df\u5f8c\u306b\u98f2\u3080\u3053\u3068\u3067\u80c3\u3078\u306e\u8ca0\u62c5\u304c\u5c11\u306a\u304f\u3001\u5b89\u5b9a\u3057\u305f\u52b9\u679c\u304c\u5f97\u3089\u308c\u308b<\/h4>\n

\u3059\u3067\u306b\u8a18\u8ff0\u3057\u307e\u3057\u305f\u304c\u3001\u7a7a\u8179\u6642\u306b\u98f2\u3080\u30b3\u30fc\u30d2\u30fc\u306f\u80c3\u9178\u5206\u6ccc\u3092\u5f37\u3081\u3001\u80c3\u306e\u4e0d\u8abf\u3092\u62db\u304d\u3084\u3059\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u4e00\u65b9\u3067\u3001\u98df\u5f8c\u306b\u30b3\u30fc\u30d2\u30fc\u3092\u98f2\u3080\u5834\u5408\u306f\u3001\u80c3\u306e\u4e2d\u306b\u98df\u3079\u7269\u304c\u5b58\u5728\u3059\u308b\u305f\u3081\u3001\u30b3\u30fc\u30d2\u30fc\u306b\u3088\u308b\u80c3\u9178\u5206\u6ccc\u306e\u523a\u6fc0\u304c\u7de9\u3084\u304b\u306b\u306a\u308a\u3084\u3059\u3044\u3068\u3055\u308c\u307e\u3059\u3002<\/p>\n

\u98df\u7269\u304c\u80c3\u7c98\u819c\u306e\u4fdd\u8b77\u30af\u30c3\u30b7\u30e7\u30f3\u3068\u306a\u308b\u3053\u3068\u3067\u3001\u80c3\u3078\u306e\u76f4\u63a5\u7684\u306a\u523a\u6fc0\u3092\u8efd\u6e1b\u3059\u308b\u50cd\u304d\u304c\u3042\u308b\u304b\u3089\u3067\u3059\u3002<\/p>\n

\u3053\u306e\u305f\u3081\u3001\u80c3\u304c\u5f31\u3044\u4eba\u3084\u80c3\u3082\u305f\u308c\u30fb\u80f8\u3084\u3051\u3092\u611f\u3058\u3084\u3059\u3044\u4eba\u306b\u3068\u3063\u3066\u306f\u3001\u7a7a\u8179\u6642\u3088\u308a\u3082\u98df\u5f8c\u306e\u30b3\u30fc\u30d2\u30fc\u6442\u53d6\u306e\u307b\u3046\u304c\u6bd4\u8f03\u7684\u5b89\u5168<\/strong>\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

Effects of Coffee on the Gastro-Intestinal Tract: A Narrative Review and Literature Update<\/a><\/p>\n

\u98df\u5f8c\u306e\u30b3\u30fc\u30d2\u30fc\u306f\u98df\u5f8c\u8840\u7cd6\u5024\u306e\u4e0a\u6607\u3092\u7de9\u3084\u304b\u306b\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b<\/h4>\n

\u30b3\u30fc\u30d2\u30fc\u306b\u542b\u307e\u308c\u308b\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u306e\u4e00\u7a2e\u300c\u30af\u30ed\u30ed\u30b2\u30f3\u9178\u300d\u306b\u306f\u3001\u809d\u81d3\u3067\u306e\u7cd6\u65b0\u751f\uff08\u4f53\u5185\u3067\u30d6\u30c9\u30a6\u7cd6\u3092\u65b0\u305f\u306b\u4f5c\u308a\u51fa\u3059\u50cd\u304d\uff09\u3092\u6291\u3048\u308b\u4f5c\u7528\u3084\u3001\u8178\u3067\u306e\u7cd6\u5438\u53ce\u306e\u30b9\u30d4\u30fc\u30c9\u3092\u3086\u308b\u3084\u304b\u306b\u3059\u308b\u52b9\u679c\u304c\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u305d\u306e\u305f\u3081\u3001\u98df\u5f8c\u306b\u30af\u30ed\u30ed\u30b2\u30f3\u9178\u3092\u591a\u304f\u542b\u3080\u30d6\u30e9\u30c3\u30af\u30b3\u30fc\u30d2\u30fc\u3092\u98f2\u3080\u3053\u3068\u3067\u3001\u6025\u6fc0\u306a\u8840\u7cd6\u5024\u306e\u4e0a\u6607\uff08\u8840\u7cd6\u5024\u30b9\u30d1\u30a4\u30af\uff09\u3092\u9632\u3050\u53ef\u80fd\u6027\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/strong><\/p>\n

\u5b9f\u969b\u306b\u3001Johnston\u3089\uff082003\uff09\u306e\u7814\u7a76\u3067\u306f\u3001\u30b3\u30fc\u30d2\u30fc\u306e\u6442\u53d6\u306b\u3088\u308aGIP\uff08\u6d88\u5316\u7ba1\u304b\u3089\u5206\u6ccc\u3055\u308c\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u50cd\u304d\u3092\u4fc3\u3059\u30db\u30eb\u30e2\u30f3\uff09\u306e\u5206\u6ccc\u304c\u6291\u3048\u3089\u308c\u3001GLP-1\uff08\u8840\u7cd6\u5024\u306e\u4e0a\u6607\u3092\u3086\u308b\u3084\u304b\u306b\u3057\u3001\u6e80\u8179\u611f\u306b\u3082\u95a2\u4e0e\u3059\u308b\u30db\u30eb\u30e2\u30f3\uff09\u306e\u5206\u6ccc\u304c\u5897\u52a0\u3059\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

\u3053\u308c\u306b\u3088\u308a\u3001\u8178\u3067\u306e\u7cd6\u306e\u5438\u53ce\u304c\u9045\u308c\u3001\u8840\u7cd6\u5024\u306e\u4e0a\u6607\u304c\u7a4f\u3084\u304b\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n

\u307e\u305f\u3001Olthof\u3089\uff082009\uff09\u306f\u3001\u30af\u30ed\u30ed\u30b2\u30f3\u9178\u3092\u542b\u3080\u30b3\u30fc\u30d2\u30fc\u3092\u98f2\u3093\u3060\u30b0\u30eb\u30fc\u30d7\u3067\u306f\u3001\u98df\u5f8c30\u5206\u306e\u8840\u7cd6\u5024\u304c\u4f4e\u304f\u306a\u3063\u305f\u3053\u3068\u3092\u5831\u544a\u3057\u3066\u304a\u308a\u3001\u8840\u7cd6\u5909\u52d5\u3092\u548c\u3089\u3052\u308b\u4f5c\u7528\u304c\u3042\u308b\u3053\u3068\u3092\u88cf\u3065\u3051\u3066\u3044\u307e\u3059\u3002<\/p>\n

Johnston et\u202fal. (2003), American Journal of Clinical Nutrition<\/a><\/p>\n

Olthof et al. (2009), Diabetes Care<\/a><\/p>\n

\u7a7a\u8179\u6642\u306e\u6442\u53d6\u306f\u80c3\u3092\u523a\u6fc0\u3057\u3084\u3059\u304f\u3001\u4f53\u8cea\u306b\u3088\u3063\u3066\u306f\u907f\u3051\u305f\u307b\u3046\u304c\u3088\u3044<\/h4>\n

\u3059\u3067\u306b\u8a18\u8ff0\u3057\u307e\u3057\u305f\u304c\u3001\u7a7a\u8179\u6642\u306b\u98f2\u3080\u30b3\u30fc\u30d2\u30fc\u306f\u80c3\u9178\u5206\u6ccc\u3092\u5f37\u3081\u3001\u80c3\u306e\u4e0d\u8abf\u3092\u62db\u304d\u3084\u3059\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u671d\u8d77\u304d\u3066\u3059\u3050\u306b\u30b3\u30fc\u30d2\u30fc\u3092\u98f2\u3080\u7fd2\u6163\u306e\u3042\u308b\u4eba\u306f\u3001\u6c34\u3084\u98df\u4e8b\u3092\u5148\u306b\u6442\u3063\u3066\u304b\u3089\u30b3\u30fc\u30d2\u30fc\u3092\u98f2\u3080\u3053\u3068\u3067\u4e0d\u8abf\u3092\u56de\u907f\u3057\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002<\/strong><\/p>\n

\u30c0\u30a4\u30a8\u30c3\u30c8\u3084\u8102\u80aa\u71c3\u713c\u76ee\u7684\u306e\u5834\u5408\u306f\u300c\u8efd\u98df\u5f8c\uff0b\u904b\u52d5\u524d\u300d\u304c\u6700\u9069<\/h4>\n

\u30c0\u30a4\u30a8\u30c3\u30c8\u3084\u8102\u80aa\u71c3\u713c\u3092\u76ee\u7684\u3068\u3059\u308b\u5834\u5408\u3001\u300c\u8efd\u304f\u98df\u4e8b\u3092\u3057\u3066\u304b\u3089\u904b\u52d5\u3059\u308b\u524d\u300d\u306b\u30ab\u30d5\u30a7\u30a4\u30f3\u3092\u6442\u53d6\u3059\u308b\u3053\u3068\u3067\u3001\u8102\u80aa\u304c\u52b9\u7387\u3088\u304f\u71c3\u713c\u3055\u308c\u308b<\/strong>\u3068\u3044\u3046\u7814\u7a76\u5831\u544a\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u305f\u3068\u3048\u3070\u3001\u3042\u308b\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\uff08\u8907\u6570\u306e\u4fe1\u983c\u6027\u306e\u9ad8\u3044\u7814\u7a76\u7d50\u679c\u3092\u7d71\u5408\u3057\u3066\u5206\u6790\u3057\u305f\u7dcf\u5408\u7814\u7a76\uff09\u3067\u306f\u3001\u8efd\u98df\u5f8c5\u6642\u9593\u4ee5\u5185\u306b\u3001\u30ab\u30d5\u30a7\u30a4\u30f3\u3092\u6442\u53d6\u3057\u305f\u5834\u5408\u3001\u904b\u52d5\u4e2d\u306b\u8102\u80aa\u9178\u306e\u9178\u5316\uff08\u8102\u80aa\u304c\u5206\u89e3\u3055\u308c\u3066\u30a8\u30cd\u30eb\u30ae\u30fc\u3068\u3057\u3066\u4f7f\u308f\u308c\u308b\u3053\u3068\uff09\u304c\u6709\u610f\u306b\u5897\u52a0\u3059\u308b\u3068\u3044\u3046\u7d50\u679c\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

Effect of Acute Caffeine Intake on Fat Oxidation Rate during Fed-State Exercise: A Systematic Review and Meta-Analysis<\/a><\/p>\n

\u30b3\u30fc\u30d2\u30fc \u52b9\u679c \uff5c\u30a4\u30f3\u30b9\u30bf\u30f3\u30c8\u3067\u3082\u52b9\u679c\u304c\u671f\u5f85\u3067\u304d\u308b<\/h3>\n

\"\"<\/h3>\n

\u30a4\u30f3\u30b9\u30bf\u30f3\u30c8\u30b3\u30fc\u30d2\u30fc\u306b\u3082\u30ab\u30d5\u30a7\u30a4\u30f3\u304c\u542b\u307e\u308c\u3066\u304a\u308a\u3001\u899a\u9192\u30fb\u96c6\u4e2d\u529b\u5411\u4e0a\u52b9\u679c\u306f\u57fa\u672c\u7684\u306b\u540c\u3058<\/h4>\n

\u30a4\u30f3\u30b9\u30bf\u30f3\u30c8\u30b3\u30fc\u30d2\u30fc1\u676f\u306b\u542b\u307e\u308c\u308b\u30ab\u30d5\u30a7\u30a4\u30f3\u306f\u3001\u30c9\u30ea\u30c3\u30d7\u30b3\u30fc\u30d2\u30fc\u306b\u6bd4\u3079\u3066\u3084\u3084\u5c11\u306a\u3044\u3082\u306e\u306e\u3001\u591a\u304f\u306e\u7814\u7a76\u3067\u300e\u5c11\u91cf\u3067\u3082\u7720\u6c17\u899a\u307e\u3057\u30fb\u6ce8\u610f\u529b\u5411\u4e0a\u30fb\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u7dad\u6301\u306b\u5341\u5206\u52b9\u679c\u304c\u3042\u308b\u300f<\/strong>\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u98df\u54c1\u6210\u5206\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u306b\u3088\u308b\u3068\u3001\u30a4\u30f3\u30b9\u30bf\u30f3\u30c8\u30b3\u30fc\u30d2\u30fc(\u9846\u7c92\u88fd\u54c1)100\uff47\u306b\u542b\u307e\u308c\u308b\u30ab\u30d5\u30a7\u30a4\u30f3\u306f4\uff47\u3068\u8a18\u8f09\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

Effects of Caffeine on Cognitive Performance, Mood, and Alertness in Sleep-Deprived Humans<\/a><\/p>\n

\u98df\u54c1\u6210\u5206\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\uff1a\u3057\u597d\u98f2\u6599\u985e\/\uff1c\u30b3\u30fc\u30d2\u30fc\u30fb\u30b3\u30b3\u30a2\u985e\uff1e\/\u30b3\u30fc\u30d2\u30fc\/\u30a4\u30f3\u30b9\u30bf\u30f3\u30c8\u30b3\u30fc\u30d2\u30fc<\/a><\/p>\n

\u30a4\u30f3\u30b9\u30bf\u30f3\u30c8\u306b\u3082\u6297\u9178\u5316\u6210\u5206\uff08\u30af\u30ed\u30ed\u30b2\u30f3\u9178\u306a\u3069\uff09\u304c\u542b\u307e\u308c\u3066\u304a\u308a\u3001\u7f8e\u808c\u30fb\u6297\u7cd6\u5316\u306a\u3069\u306e\u52b9\u679c\u3082\u671f\u5f85\u3067\u304d\u308b<\/h4>\n

Budryn\u3089\uff082009\uff09\u306e\u5206\u6790\u3067\u306f\u3001\u30a4\u30f3\u30b9\u30bf\u30f3\u30c8\u30b3\u30fc\u30d2\u30fc\u52a0\u5de5\u6642\u306b\u3082\u30af\u30ed\u30ed\u30b2\u30f3\u9178\u306a\u3069\u6297\u9178\u5316\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u304c\u4fdd\u6301\u3055\u308c\u3066\u304a\u308a\u3001<\/strong>\u305d\u306e\u6297\u9178\u5316\u529b\u304c\u88fd\u54c1\u306b\u6b8b\u308b<\/strong>\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u307e\u305f\u3001\u5225\u306e\u7814\u7a76\u3067\u306f\u3001\u30af\u30ed\u30ed\u30b2\u30f3\u9178\u304c\u7d2b\u5916\u7dda\u306b\u3088\u308b\u76ae\u819a\u306e\u9178\u5316\u30c0\u30e1\u30fc\u30b8\u3084\u8272\u7d20\u6c88\u7740\u3092\u6291\u3048\u308b\u53ef\u80fd\u6027\u304c\u5831\u544a\u3055\u308c\u3001\u30a4\u30f3\u30b9\u30bf\u30f3\u30c8\u30b3\u30fc\u30d2\u30fc\u306b\u3082\u7f8e\u808c\u30fb\u6297\u7cd6\u5316\u306a\u3069\u306e\u52b9\u679c\u304c\u671f\u5f85\u3067\u304d\u308b\u3053\u3068\u304c\u88cf\u4ed8\u3051\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

Development of an instant coffee enriched with chlorogenic acids<\/a><\/p>\n

Instant coffee with high chlorogenic acid levels protects humans against oxidative damage of macromolecules<\/a><\/p>\n

\u30ab\u30d5\u30a7\u30a4\u30f3\u91cf\u30fb\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u91cf\u306f\u88fd\u54c1\u306b\u3088\u3063\u3066\u3070\u3089\u3064\u304d\u304c\u3042\u308b<\/h4>\n

\u88fd\u54c1\u3054\u3068\u306b\u4f7f\u7528\u3059\u308b\u8c46\u306e\u7a2e\u985e\u30fb\u88fd\u6cd5\u30fb\u6fc3\u5ea6\u304c\u7570\u306a\u308b\u305f\u3081\u3001\u540c\u3058\u30a4\u30f3\u30b9\u30bf\u30f3\u30c8\u3067\u3082\u30ab\u30d5\u30a7\u30a4\u30f3\u91cf\u3084\u6297\u9178\u5316\u6210\u5206\u306b\u5dee\u304c\u3042\u308b\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u52b9\u679c\u3092\u6c42\u3081\u308b\u306a\u3089\u3001\u7121\u7cd6\u30fb\u7121\u6dfb\u52a0\u306e\u30d4\u30e5\u30a2\u30bf\u30a4\u30d7\u3092\u9078\u3073\u3001\u6fc3\u3055\u3092\u6fc3\u3044\u76ee\u306b\u8abf\u6574\u3059\u308b<\/strong>\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n

\uff08Crozier et al., Food and Function, 2012\uff09<\/a><\/p>\n

\u307e\u3068\u3081<\/h2>\n

\u3053\u306e\u8a18\u4e8b\u3092\u901a\u3058\u3066\u3001\u30b3\u30fc\u30d2\u30fc\u304c\u5065\u5eb7\u30fb\u7f8e\u5bb9\u30fb\u4ee3\u8b1d\u3068\u3044\u3063\u305f\u5e45\u5e83\u3044\u9762\u3067\u3001\u79d1\u5b66\u7684\u306a\u6839\u62e0\u306b\u57fa\u3065\u3044\u305f\u52b9\u679c\u3092\u3082\u305f\u3089\u3059\u3053\u3068\u304c\u304a\u5206\u304b\u308a\u3044\u305f\u3060\u3051\u305f\u304b\u3068\u601d\u3044\u307e\u3059\u3002
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