{"id":15353,"date":"2024-04-28T14:09:12","date_gmt":"2024-04-28T05:09:12","guid":{"rendered":"https:\/\/www.acacia-no-ki.co.jp\/wellness\/?p=15353"},"modified":"2024-04-28T14:09:12","modified_gmt":"2024-04-28T05:09:12","slug":"acaciapolyphenol-safety","status":"publish","type":"post","link":"https:\/\/www.acacia-no-ki.co.jp\/wellness\/acaciapolyphenol-safety\/","title":{"rendered":"\u30a2\u30ab\u30b7\u30a2\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u306e\u5b89\u5168\u6027\u306b\u95a2\u3059\u308b\u8a66\u9a13\u7814\u7a76"},"content":{"rendered":"

\u30a2\u30ab\u30b7\u30a2\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u306e\u5b89\u5168\u6027\u3092\u8a3c\u660e\u3059\u308b\u305f\u3081\u306b\u30d2\u30c8\u81e8\u5e8a\u8a66\u9a13\u3092\u5b9f\u65bd\u3057\u3066\u3044\u308b\u3063\u3066\u30db\u30f3\u30c8\uff1f<\/h2>\n

\u2192\u30db\u30f3\u30c8\uff08\u4fe1\u983c\u6027\u2605\u2605\u2605\u2605\u2605\uff09\uff1a\u30a2\u30ab\u30b7\u30a2\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u306f\u98df\u54c1\u3068\u3057\u3066\u306e\u5b89\u5168\u6027\u3092\u8a3c\u660e\u3059\u308b\u305f\u3081\u306b\u4f55\u5ea6\u3082\u30d2\u30c8\u81e8\u5e8a\u8a66\u9a13\u3092\u5b9f\u65bd\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u7b2c21\u56de\u3000\u30a2\u30ab\u30b7\u30a2\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u306e\u5b89\u5168\u6027\u306b\u95a2\u3059\u308b\u30a6\u30ef\u30b5\u306e\u771f\u76f8<\/p>\n

1. \u30a2\u30ab\u30b7\u30a2\u6a39\u76ae\u62bd\u51fa\u7269\u306e\u904e\u5270\u6442\u53d6\u306b\u3088\u308b\u5b89\u5168\u6027\u8a66\u9a13\uff08\u30d2\u30c8\u81e8\u5e8a\u8a66\u9a13\uff09<\/h3>\n

\u30a2\u30ab\u30b7\u30a2\u306e\u6a39\u3067\u306f\u300c\u30a2\u30ab\u30b7\u30a2\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u300d\u306e\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306e\u767a\u58f2\u4ee5\u524d\u304b\u3089\u81e8\u5e8a\u8a66\u9a13\u3067\u306e\u5b89\u5168\u6027\u3092\u78ba\u8a8d\u3057\u3066\u304d\u307e\u3057\u305f\u3002\u305d\u3057\u3066\u3001\u5546\u54c1\u3068\u3057\u3066\u8ca9\u58f216\u5e74\u304c\u7d4c\u3061\u307e\u3057\u305f\u304c\u4eca\u65e5\u307e\u3067\u7686\u69d8\u306b\u5b89\u5fc3\u3057\u3066\u304a\u98f2\u307f\u3044\u305f\u3060\u3044\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n

\u79c1\u305f\u3061\u306f\u30a2\u30ab\u30b7\u30a2\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u306e\u5b89\u5168\u6027\u3092\u8a3c\u660e\u3059\u308b\u305f\u3081\u306b\u4f55\u5ea6\u3082\u30d2\u30c8\u81e8\u5e8a\u8a66\u9a13\u3092\u5b9f\u65bd\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u5c0f\u5ddd\u3001\u4e09\u6d66\uff082017<\/a>\uff09\u306e\u7814\u7a76\u3067\u306f29\u540d\u306e\u88ab\u9a13\u8005\u306b\u8a66\u9a13\u98df\u54c1\u3092\u6442\u53d6\u3057\u3066\u3082\u3089\u3044\u6442\u53d6\u958b\u59cb2 \u9031\u5f8c\u3001\u6442\u53d6\u958b\u59cb4 \u9031\u5f8c\u3001\u304a\u3088\u3073\u6442\u53d6\u7d42\u4e86\u5f8c\u306e\u5f8c\u89b3\u5bdf2 \u9031\u5f8c\u306b\u554f\u8a3a\u3001\u7406\u5b66\u691c\u67fb\u3001\u81e8\u5e8a\u691c\u67fb\u7b49\u306e\u5404\u691c\u67fb\u3067\u8a55\u4fa1\u3057\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001\u554f\u984c\u3068\u306a\u308b\u7570\u5e38\u6240\u898b\u306f\u8a8d\u3081\u3089\u308c\u307e\u305b\u3093\u3067\u3057\u305f\uff081\uff09\u3002<\/p>\n

\u3053\u306e\u8a66\u9a13\u306e\u30a2\u30ab\u30b7\u30a2\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u306e\u91cf\u306f\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306b\u4f7f\u7528\u4f3c\u3066\u3044\u308b\u4e00\u65e5\u306e\u6442\u53d6\u76ee\u5b89\u91cf\u306e5\u500d\u4ee5\u4e0a\u306e\u91cf\u3067\u3059\u3002<\/p>\n

\u307e\u305f\u7247\u5ca1\u3089\uff082011\uff09<\/a>\u3067\u306f\uff14\u3064\u306e\u5b89\u5168\u6027\u81e8\u5e8a\u8a66\u9a13\u3092\u307e\u3068\u3081\u305f\u8ad6\u6587\u3092\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002\u8a66\u9a13\u2460\u3067\u306f\u88ab\u9a13\u800520\u540d\u30925\u540d\u305a\u30644\u7fa4\u306b\u7d44\u307f\u5165\u308c\u3001\u5404\u88ab\u9a13\u8005\u306b\u30a2\u30ab\u30b7\u30a2\u6a39\u76ae\u62bd\u51fa\u7269\u3092\u305d\u308c\u305e\u308c250\u3001500\u3001750\u30011000mg\u6442\u53d6\u3057\u307e\u3057\u305f\u3002\u8a66\u9a13\u2461\u3067\u306f\u3001\u88ab\u9a13\u80055\u540d\u306b\u3001\u30a2\u30ab\u30b7\u30a2\u6a39\u76ae\u62bd\u51fa\u7269\u30921500mg\u6442\u53d6\u3057\u307e\u3057\u305f\u3002\u8a66\u9a13\u2462\u3067\u306f\u3001\u88ab\u9a13\u800522\u540d\u309211\u540d\u305a\u30642\u7fa4\u306b\u304f\u307f\u3044\u308c\u3001\u5404\u7fa4\u88ab\u9a13\u8005\u306b\u30a2\u30ab\u30b7\u30a2\u6a39\u76ae\u62bd\u51fa\u7269\u30921\u65e5\u3042\u305f\u308a250mg\u3001500mg\u6442\u53d6\u3055\u305b\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u8a66\u9a13\u2463\u3067\u306f\u3001\u88ab\u9a13\u800525\u540d\u309211\u540d\u306814\u540d\u306e2\u7fa4\u306b\u7d44\u307f\u5165\u308c\u3001\u30a2\u30ab\u30b7\u30a2\u6a39\u76ae\u62bd\u51fa\u7269\u30921\u65e5\u3042\u305f\u308a750mg\u30011000mg\u6442\u53d6\u3055\u305b\u305f\u3002\u8a66\u9a13\u2460\u2461\u306f\u77ed\u671f\u6295\u4e0e\u3068\u3057\u3001\u2462\u2463\u306f4\u9031\u9593\u306e\u6442\u53d6\u3068\u3057\u307e\u3057\u305f\u3002<\/p>\n

\u3044\u305a\u308c\u306e\u8a66\u9a13\u306b\u304a\u3044\u3066\u3082\u554f\u984c\u3068\u306a\u308b\u6240\u898b\u306f\u898b\u3089\u308c\u305a\u3001\u30a2\u30ab\u30b7\u30a2\u6a39\u76ae\u62bd\u51fa\u7269\u304a\u3088\u3073\u30a2\u30ab\u30b7\u30a2\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u304c\u6975\u3081\u3066\u5b89\u5168\u6027\u306e\u9ad8\u3044\u539f\u6599\u3067\u3042\u308b\u3053\u3068\u304c\u8a3c\u660e\u3055\u308c\u307e\u3057\u305f\uff082\uff09\u3002\u3055\u3089\u306b\u3001\u3053\u308c\u307e\u3067\u884c\u3063\u305f\u6a5f\u80fd\u6027\u8868\u793a\u98df\u54c1\u306e\u7533\u8acb\u306b\u5fc5\u8981\u306a\u30d2\u30c8\u81e8\u5e8a\u8a66\u9a13\u306b\u304a\u3044\u3066\u3082\u6709\u5bb3\u4e8b\u9805\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\uff08\uff13,\uff14,\uff15,\uff16\uff09\u3002<\/p>\n

\u79c1\u305f\u3061\u306f\u30a2\u30ab\u30b7\u30a2\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u306e\u5b89\u5168\u6027\u3092\u8a3c\u660e\u3059\u308b\u305f\u3081\u306b\u4f55\u5ea6\u3082\u30d2\u30c8\u81e8\u5e8a\u8a66\u9a13\u3092\u5b9f\u65bd\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

2.\u3000\u30a2\u30ab\u30b7\u30a2\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u306e\u751f\u7523\u4f53\u5236<\/h3>\n

2-1.\u3000\u5fb9\u5e95\u3057\u305f\u54c1\u8cea\u7ba1\u7406\u3068\u3001\u82d7\u6728\u304b\u3089\u306e\u4e00\u8cab\u751f\u7523\u3092\u5b9f\u73fe<\/h4>\n

\u30a2\u30ab\u30b7\u30a2\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u306e\u539f\u6599\u3068\u306a\u308b\u30a2\u30ab\u30b7\u30a2\u306f\u3001\u82d7\u6728\u304b\u3089\u306e\u4e00\u8cab\u751f\u7523\u3092\u5b9f\u65bd\u3057\u3066\u3044\u307e\u3059\u3002\u7121\u8fb2\u85ac\u3067\u306e\u683d\u57f9\u306f\u3082\u3061\u308d\u3093\u3001\u53ce\u7a6b\u3068\u690d\u6797\u306e\u30b5\u30a4\u30af\u30eb\u3092\u8a08\u753b\u7684\u306b\u7ba1\u7406\u3059\u308b\u3053\u3068\u3067\u3001\u5b89\u5b9a\u4f9b\u7d66\u3092\u5b9f\u73fe\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u3057\u3066\u3001\u5fb9\u5e95\u3057\u305f\u54c1\u8cea\u7ba1\u7406\u306e\u3082\u3068\u5b89\u5168\u306a\u751f\u7523\u4f53\u5236\u3092\u78ba\u7acb\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

2-2. \u6c34\u8cea\u691c\u67fb\u3092\u30d1\u30b9\u3057\u305f\u30af\u30ea\u30fc\u30f3\u306a\u6c34\u3067\u62bd\u51fa<\/h4>\n

\"\"<\/p>\n

\u53ce\u7a6b\u671f\u306b\u306a\u308b\u3068\u3001\u8fb2\u5bb6\u306e\u65b9\u3005\u306e\u624b\u4f5c\u696d\u306b\u3088\u308a\u30a2\u30ab\u30b7\u30a2\u306e\u6210\u6728\u306e\u6a39\u76ae\u306f1\u679a\u305a\u3064\u5265\u304b\u308c\u3066\u3044\u304d\u307e\u3059\u3002\u305d\u306e\u5f8c\u3001\u6a39\u76ae\u3092\u7c89\u7815\u3057\u3001\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306e\u539f\u6599\u3068\u306a\u308b\u6210\u5206\u3092\u71b1\u6c34\u3067\u62bd\u51fa\u3057\u307e\u3059\u3002\u5b89\u5168\u6027\u3092\u4fdd\u8a3c\u3059\u308b\u691c\u67fb\u57fa\u6e96\u3092\u6e80\u305f\u3057\u305f\u6c34\u306e\u307f\u4f7f\u7528\u3057\u3001\u6709\u6a5f\u6eb6\u5a92\u3084\u85ac\u54c1\u306f\u4e00\u5207\u4f7f\u7528\u3057\u3066\u3044\u307e\u305b\u3093\u3002\u30a2\u30ab\u30b7\u30a2\u539f\u6599\u306e\u751f\u7523\u306b\u306f\u767a\u9175\u306a\u3069\u306e\u5fae\u751f\u7269\u3084\u30ab\u30d3\u985e\u306e\u95a2\u4e0e\u3059\u308b\u884c\u7a0b\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u6975\u3081\u3066\u5b89\u5168\u306a\u71b1\u6c34\u306b\u3088\u308b\u62bd\u51fa\u6cd5\u3067\u3059\u3002<\/p>\n

2-3. \u6700\u65b0\u92ed\u306e\u6a5f\u5668\u3092\u5b8c\u5099\u3057\u305f\u56fd\u5185\u5de5\u5834\u3067\u751f\u7523<\/h4>\n

\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3078\u306e\u52a0\u5de5\u306e\u884c\u7a0b\u306f\u3001\u6700\u65b0\u92ed\u306e\u6a5f\u5668\u3092\u53d6\u308a\u63c3\u3048\u308b\u56fd\u5185\u5de5\u5834\u3067\u88fd\u9020\u3057\u3066\u3044\u307e\u3059\u3002\u65e5\u672c\u5065\u5eb7\u30fb\u6804\u990a\u98df\u54c1\u5354\u4f1a\u304c\u5b9a\u3081\u308bGMP\u8a8d\u5b9a\u5de5\u5834\u3068\u63d0\u643a\u3092\u7d50\u3073\u300130\u9805\u76ee\u304b\u3089\u306a\u308b\u53b3\u683c\u306a\u691c\u67fb\u57fa\u6e96\u306e\u3082\u3068\u30011\u7c92\u305a\u3064\u76ee\u8996\u3067\u54c1\u8cea\u3092\u78ba\u8a8d\u3059\u308b\u4f53\u5236\u3092\u6574\u3048\u5916\u90e8\u306e\u5c02\u9580\u6a5f\u95a2\u306b\u3082\u5b89\u5168\u6027\u8a66\u9a13\u306e\u5b9f\u65bd\u3092\u4f9d\u983c\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\"\"<\/p>\n

\u307e\u3068\u3081<\/h3>\n

\u30a2\u30ab\u30b7\u30a2\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u306e\u5b89\u5168\u6027\u306f\u8907\u6570\u306e\u81e8\u5e8a\u8a66\u9a13\u3067\u8a3c\u660e\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3068\u3057\u3066\u306e\u88fd\u9020\u904e\u7a0b\u306b\u304a\u3044\u3066\u3082\u6700\u9ad8\u6c34\u6e96\u306e\u5b89\u5168\u6027\u3067\u751f\u7523\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u53c2\u8003\u6587\u732e<\/p>\n

1.\u5c0f\u5ddd\u58ee\u4ecb. (2017). \u30a2\u30ab\u30b7\u30a2\u6a39\u76ae\u62bd\u51fa\u7269\u306e\u30d2\u30c8\u3067\u306e\u904e\u5270\u6442\u53d6\u306b\u304a\u3051\u308b\u5b89\u5168\u6027\u8a55\u4fa1\u8a66\u9a13\u2015\u30d7\u30e9\u30bb\u30dc\u5bfe\u7167\u4e8c\u91cd\u76f2\u691c\u7121\u4f5c\u70ba\u5316\u4e26\u884c\u7fa4\u9593\u6bd4\u8f03\u8a66\u9a13\u2015.\u00a0\u85ac\u7406\u3068\u6cbb\u7642<\/i>,\u00a045<\/i>(12), 1927-1934.<\/a><\/p>\n

2.\u30a2\u30ab\u30b7\u30a2\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u542b\u6709\u98df\u54c1\u306e\u5b89\u5168\u6027\u3000\u5065\u5e38\u7537\u6027\u6210\u4eba\u306b\u304a\u3051\u308b\u5b89\u5168\u6027\u8a55\u4fa1\u8a66\u9a13. <\/span>\u7247\u5ca1 \u6b66\u53f8, \u5c0f\u5ddd \u58ee\u4ecb,\u00a0\u677e\u524d \u667a\u4e4b,\u00a0\u77e2\u5d0e \u7fa9\u548c,\u00a0\u5c71\u53e3 \u82f1\u4e16. (2011) \u30a2\u30ab\u30b7\u30a2\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u542b\u6709\u98df\u54c1\u306e\u5b89\u5168\u6027\u3000\u5065\u5e38\u7537\u6027\u6210\u4eba\u306b\u304a\u3051\u308b\u5b89\u5168\u6027\u8a55\u4fa1\u8a66\u9a13. <\/span>\u5fdc\u7528\u85ac\u7406 80, 43-52.<\/a><\/p>\n

3.Takeda R, Ogawa S, Miura N, Sawabe A: Suppressive effect of acacia polyphenol on postprandial blood glucose elevation in non-diabetic individuals: -A randomized, double-blind, placebo-controlled crossover study. Japanese Pharmacol Ther 2016, 44 (10): 1463\u20131469<\/a><\/p>\n

4. Hoshino, T., Yamashita, S. I., Suzuki, N., Baba, A., Ogawa, S., & Izumi, T. (2019). Impact of Acacia bark extract tablets on the skin of healthy humans: a randomized, double-blind, placebo-controlled study.\u00a0Bioscience, biotechnology, and biochemistry<\/i>,\u00a083<\/i>(3), 538-550.<\/a><\/p>\n

5. Baba, A., Hoshino, T., Ogawa, S., & Takara, T. (2021). Improvement of glucose metabolism and safety of acacia bark-derived proanthocyanidins in healthy Japanese adults: A Randomized, Double-blind, Placebo-controlled, Parallel-group Trial.\u00a0Functional Foods in Health and Disease<\/i>,\u00a011<\/i>(9), 431-455.<\/a><\/p>\n

6. Baba, A., Hoshino, T., Ogawa, S., & Takara, T. (2021). Effects of the consumption of proanthocyanidins derived from acacia bark on blood pressure in healthy Japanese adults: A randomized, double-blind, placebo-controlled, parallel-group comparison study.\u00a0Functional Foods in Health and Disease<\/i>,\u00a011<\/i>(7), 310-332.<\/a><\/p>\n

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 <\/p>\n

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